{"id":6686,"date":"2018-06-11T11:55:15","date_gmt":"2018-06-11T09:55:15","guid":{"rendered":"http:\/\/www.phytocontrol.com\/?p=6686"},"modified":"2018-06-11T11:55:15","modified_gmt":"2018-06-11T09:55:15","slug":"consumer-toxicological-risk-assessment","status":"publish","type":"post","link":"https:\/\/www.phytocontrol.com\/en\/news\/consumer-toxicological-risk-assessment\/","title":{"rendered":"Consumer toxicological risk assessment"},"content":{"rendered":"<div class=\"hover_box\"><div class=\"hover_box_wrapper\"><img decoding=\"async\" class=\"scale-with-grid visible_photo\" src=\"\/wp-content\/uploads\/2018\/06\/assiette-consommateur-700-400-1.jpg\" alt=\"Consumer toxicological risk assessment\" width=\"\" height=\"\"\/><img decoding=\"async\" class=\"scale-with-grid hidden_photo\" src=\"\/wp-content\/uploads\/2018\/06\/vegetables-700-400-1.jpg\" alt=\"Consumer toxicological risk assessment\" width=\"\" height=\"\"\/><\/div><\/div>\n\n<p>&nbsp;<\/p>\n<p>For the control of pesticide residues in foodstuffs, the applicable regulation is Regulation (EU) No 396\/2005 and its successive amendments.<br \/>\nThis text defines the Maximum Residue Limits (MRLs) for each pesticide-commodity pair expressed in mg\/kg. Regulatory residue definitions may include both a single residue and a sum of associated residues and metabolites.<br \/>\nThese residue definitions are frequently revised and their implementation requires a substantial material and human investment that our laboratory makes a point of honour to respect.<br \/>\nMRLs are used to determine the compliance or non-compliance of a sample.<br \/>\nIn the case of a non-compliant sample, exceeding the MRL does not necessarily imply a toxicological risk for the consumer.<\/p>\n<p>A calculation can be made to assess the acute toxicological risk to the consumer.<br \/>\nThis assessment compares the toxicity data of the pesticide, the Acute reference Dose (ArfD) with an MRL exceedance with an estimate of the short-term consumption of the non-compliant commodity.<\/p>\n<p>Below, the various parameters taken into account in the evaluation:<\/p>\n<p><strong>Arfd:<\/strong> Acute reference dose expressed in milligrams of active substance per kilogram of body weight. It is a toxicological data which corresponds to the maximum quantity of the detected pesticide which can be ingested by the consumer during a day without risk for his health. This value is the reference point in assessing the risk to the consumer.<\/p>\n<p>The following parameters are used to estimate the amount of the pesticide in excess that would be ingested by the consumer (ITSP or IESTI):<br \/>\n<strong>LP:<\/strong> Large Portion, expressed in kg\/day and corresponds to 97.5 percentile consumption for the commodity in question.<br \/>\n<strong>U:<\/strong> Unit weight of the commodity expressed in kg.<br \/>\n<strong>FV:<\/strong> Variability factor depending on the unit weight of the commodity.<br \/>\n<strong>PF:<\/strong> Processing factor or Peeling factor (determined as the ration of residues in the processed\/peeled product divided by the concentration of residues in the unprocessed\/unpeeled product). This data is not available for all pesticide\/product pairs.<br \/>\nbw: Average body weight.<\/p>\n<p>The estimated consumption value (PSTI\/IESTI) and the toxicological reference data (ARfD) are then compared:<br \/>\nIf <strong>PSTI&lt;ARfD:<\/strong> No risk to the consumer.<br \/>\nIf <strong>PSTI&gt;ARfD<\/strong>: Consumer risk.<\/p>\n<p>Thus when a proven risk for the consumer is identified, the case must be notified by the authorities and will be relayed to the RASFF website (EU Food Alert System).<\/p>\n<p>Please be aware that your Phytocontrol laboratory is able to carry out this evaluation on request.<\/p>\n<p>For more information, you can consult the following document:<\/p>\n<p>RASFF WI 2.2: <a href=\"https:\/\/ec.europa.eu\/food\/sites\/food\/files\/safety\/docs\/rasff_reg-guid_sops_wi-2-2_en.pdf\">Guidelines for the calculation of consumer intake and evaluation of the risk for pesticide residues.<\/a><\/p>\n<p>For any further information, do not hesitate to contact us.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; For the control of pesticide residues in foodstuffs, the applicable regulation is Regulation (EU) No 396\/2005 and its successive amendments. This text defines the Maximum<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":2,"featured_media":6681,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[180],"tags":[],"yst_prominent_words":[],"class_list":["post-6686","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/posts\/6686","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/comments?post=6686"}],"version-history":[{"count":0,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/posts\/6686\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/media\/6681"}],"wp:attachment":[{"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/media?parent=6686"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/categories?post=6686"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/tags?post=6686"},{"taxonomy":"yst_prominent_words","embeddable":true,"href":"https:\/\/www.phytocontrol.com\/en\/wp-json\/wp\/v2\/yst_prominent_words?post=6686"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}